This paper chronicles the development of business interruption (BI) insurance in the U.S. The origin of modern-day BI insurance is traced as it evolved from so-called “profits insurance” in the United Kingdom (UK) and an endorsement to basic fire insurance policies in the U.S. to stand-alone BI insurance as it is known today. This paper identifies significant legal rulings and insurance catastrophes that have served as inflection points for the development of BI insurance, as well as major policy formats that have provided cover for the disruption of business. More recently, various forms of BI insurance have become commonplace. Standalone policies provide cover for “standard” perils, while endorsements to risk-specific policies (e.g., cyber risk) provide business income coverage for non-standard risks. Of late, business interruption claims brought about by cyberattacks and global pandemics have been of interest to industry participants. The comprehensive review of the history of BI insurance provided in this paper offers a firm foundation for ensuring thoughtful product development and insurance regulatory decisions that will support the continued evolution and availability of this important coverage.